How to Treat HER2+ Breast Cancer - Discussion with Dr. Sarah Sammons
Oncology Brothers: Practice-Changing Cancer Discussions - A podcast by Oncology Brothers

In this episode of the Oncology Brothers podcast, Drs. Rohit and Rahul Gosain welcome Dr. Sarah Sammons from Dana-Farber Cancer Institute to discuss the treatment landscape for HER2-positive breast cancer. Building on their previous discussions about triple-negative breast cancer, Drs. Gosain and Sammons dive deep into the treatment algorithms for early-stage, locally advanced, and metastatic HER2-positive breast cancer. Key topics include:• Treatment paradigms for early-stage HER2-positive breast cancer, including the APT trial and considerations for neoadjuvant therapy.• The standard of care for locally advanced disease with TCHP and managing associated toxicities.• Insights into the latest data from the PATINA trial and its implications for metastatic HER2-positive patients.• Discussion on the use of T-DXd and other treatment options in the second and third-line settings, especially for patients with brain metastases. Join us for an informative conversation filled with clinical pearls and practical insights that can help guide treatment decisions in HER2-positive breast cancer. Don't forget to like, subscribe, and check out our other episodes in the treatment algorithm series!#OncologyBrothers #HER2Positive #BreastCancer #BreastCancerTreatment #CancerPodcast #DanaFarber YouTube: https://youtu.be/_y0xSxJTptw Follow us on social media:• X/Twitter: https://twitter.com/oncbrothers• Instagram: https://www.instagram.com/oncbrothers